VEO (Value, Evidence, and Outcomes)

Definition

VEO is the discipline within a pharmaceutical or biotech company that fuses clinical efficacy data, health-economic modelling, and real-world outcomes into a single value narrative. Its remit is to demonstrate—quantitatively and credibly—that a therapy not only works but delivers meaningful health benefits at a justifiable cost, satisfying regulators, payers, clinicians, and, ultimately, patients.

Strategic Role

By uniting Medical Affairs, Health Economics & Outcomes Research (HEOR), and Market Access, VEO turns fragmented data into an integrated evidence package. This package underpins approval submissions, reimbursement negotiations, treatment-guideline inclusion, and post-launch positioning—making VEO a linchpin for timely patient access and sustained commercial success.

Core Pillars

• Value – Articulate how the therapy addresses unmet need, improves quality of life, or reduces total cost of care.
• Evidence – Generate and curate late-phase trials, real-world studies, and economic models that withstand HTA and payer scrutiny.
• Outcomes – Track and publish real-world performance, feeding back insights that support label expansions, pricing reviews, or updated treatment pathways.

Lifecycle Contribution

During development, VEO flags evidence gaps early enough to influence endpoint choice and comparator selection. At launch, it supplies robust value dossiers and budget-impact models that speed formulary adoption. In maturity, the function mines electronic health records and registries to show long-term effectiveness, safeguarding market share against new entrants.

Success Metrics

• Reimbursement win-rate—percentage of HTA or payer submissions securing favourable coverage within target timelines.
• Evidence-gap closure—proportion of high-priority gaps addressed inside 12 months of identification.
• Real-world evidence uptake—frequency with which VEO studies are cited in guidelines, payer reviews, or peer publications.